\The delicate skin under the eyes is often one of the first areas to show signs of aging. Dark circles, fine lines, and hollowing can make you look tired and older than you feel. To combat these issues, many turn to cosmetic treatments. Among the most innovative and natural options are Platelet-Rich Plasma (PRP) and Platelet-Rich Fibrin (PRF). In this blog, we will explore the differences between PRP and PRF, delve into their benefits for undereye rejuvenation, and explain why PRF stands out as a superior option, especially when compared to traditional fillers.

Understanding PRP (Platelet-Rich Plasma)

PRP therapy involves drawing a small amount of the patient’s blood, which is then spun in a centrifuge to separate the plasma from the other blood components. This plasma, rich in platelets, is then injected into the undereye area. PRP is known for its high concentration of growth factors, which can stimulate collagen production and improve skin texture.

Benefits of PRP for Undereye Rejuvenation:

  • Natural Healing: PRP uses your own blood, reducing the risk of allergic reactions and adverse effects.
  • Collagen Stimulation: Promotes the production of collagen, improving skin elasticity and thickness, which can reduce the appearance of fine lines and wrinkles.
  • Minimal Downtime: Generally, there is little to no recovery time needed after the procedure, making it a convenient option for those with busy lifestyles.
  • Improved Skin Texture: The growth factors in PRP can enhance skin texture, making the undereye area look smoother and more youthful.

Understanding PRF (Platelet-Rich Fibrin)

PRF is an advanced version of PRP, offering even greater benefits for undereye rejuvenation. PRF is also derived from the patient’s blood but is processed differently. The blood is spun at a slower speed without the addition of anticoagulants, resulting in a fibrin matrix that contains a higher concentration of platelets, leukocytes (white blood cells), and mesenchymal stem cells.

Benefits of PRF for undereye Rejuvenation:

  • Higher Concentration of Healing Factors: PRF contains more growth factors and healing cells than PRP, making it more effective in stimulating tissue regeneration.
  • Natural Fibrin Matrix: The fibrin scaffold helps to sustain the release of growth factors over time, leading to longer-lasting results and enhanced skin rejuvenation.
  • Enhanced Regeneration: The presence of leukocytes and stem cells boosts the body’s natural healing processes, improving skin quality more effectively and reducing inflammation.

PRF vs. Traditional Fillers

Traditional dermal fillers, such as those made from hyaluronic acid, are popular for adding volume and smoothing wrinkles. However, they primarily act as space-fillers and do not contribute to long-term skin health or rejuvenation. Here’s why PRF stands out as a better option:

Long-Lasting and Natural Results:

  • Sustained Release of Growth Factors: PRF’s fibrin matrix ensures a gradual and sustained release of growth factors, promoting continuous healing and rejuvenation over several months.
  • Natural Tissue Regeneration: Unlike fillers, which simply add volume, PRF stimulates the body’s own healing processes to improve skin quality from within, leading to more natural and lasting improvements.
  • Reduced Risk of Complications: Since PRF is derived from your own blood, there is minimal risk of allergic reactions or other adverse effects often associated with synthetic fillers.

The Procedure: What to Expect

The process for PRF treatment is straightforward and minimally invasive:

  1. Blood Draw: A small amount of blood is drawn from the patient, similar to a routine blood test.
  2. Centrifugation: The blood is placed in a centrifuge and spun at a slow speed to separate the PRF from other blood components.
  3. Injection: The PRF is then injected into the undereye area using fine needles. The treatment is typically quick, taking about 45 minutes to an hour.
  4. Post-Treatment Care: Patients may experience mild swelling or redness immediately after the procedure, but these effects are usually short-lived. There is minimal downtime, and most patients can return to their normal activities shortly after treatment.

Results and Maintenance

Patients typically begin to see improvements in the undereye area within a few weeks of treatment, with continued enhancement over the following months as collagen production increases and skin quality improves. Results from PRF treatments can last anywhere from six months to a year, depending on individual factors such as skin type and lifestyle.

For optimal results, multiple sessions may be recommended. Your practitioner will develop a personalized treatment plan based on your specific needs and goals.

Key Takeaways

When it comes to undereye rejuvenation, PRF offers a revolutionary approach that goes beyond the capabilities of traditional fillers and even its predecessor, PRP. By harnessing the power of your body’s natural healing processes, PRF provides a safe, effective, and long-lasting solution to undereye concerns. Its ability to improve skin quality from within makes it an ideal choice for those seeking a more youthful and refreshed appearance.

If you’re considering an undereye treatment, consult with a qualified practitioner to determine if PRF is the right option for you. Embrace the future of skincare with PRF and experience the benefits of natural, holistic rejuvenation.


1. What are the main differences between PRP and PRF for undereye treatments?

PRP is created by spinning blood at high speeds, resulting in plasma rich in platelets but without a fibrin matrix. PRF is spun at a slower speed without anticoagulants, forming a fibrin matrix with higher concentrations of platelets, leukocytes, and stem cells. This matrix releases growth factors slowly, providing longer-lasting results and better skin regeneration.

2. How do PRP and PRF compare to traditional dermal fillers in terms of results and safety?

PRP and PRF stimulate the body’s natural healing, offering longer-lasting and more natural results than traditional fillers, which mainly add volume. PRF, especially, reduces the risk of allergic reactions and adverse effects, as it’s derived from the patient’s own blood. Traditional fillers may have risks like allergic reactions and lumps.

3. What can I expect during and after a PRF treatment for undereye rejuvenation?

PRF treatment involves drawing blood, spinning it to separate PRF, and injecting it into the undereye area. The procedure takes about an hour, with minimal downtime. Mild swelling or redness may occur but subsides quickly. Results appear over weeks as collagen builds, lasting six months to a year. Multiple sessions may be recommended.